What are the primary cryoprotectant compounds produced by P. isabella for freeze tolerance?

Answer

Glucose and glycerol

The remarkable ability of the Woolly Bear to survive being frozen solid relies on actively managed biochemical processes, specifically the production of natural cryoprotectants within its body fluids. The key compounds responsible for this biological antifreeze effect are glucose and glycerol. These substances work by significantly lowering the freezing point of the water contained inside the caterpillar's body, allowing ice formation externally while preventing catastrophic internal ice crystal growth, thereby ensuring physiological survival even when external temperatures drop far below zero degrees Celsius.

What are the primary cryoprotectant compounds produced by P. isabella for freeze tolerance?
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