How does the toxicity of the venom in P. leopoldi change as the ray ages?

Answer

The toxicity decreases as the ray ages

Although the venom found in the dentine spines of the Xingu River Ray maintains a consistent composition throughout the ray's life cycle, its potency is not static. The chemical properties dictate that the actual toxicity level decreases as the ray matures and ages. This is an interesting characteristic of the species' defense mechanism, which is further complicated by a biological cycle where the ray must periodically regenerate this organ by shedding its sting, an event that occurs approximately every six months.

How does the toxicity of the venom in P. leopoldi change as the ray ages?
biologyRayfishcharacteristicriver