Which specific white patterning in ferrets is linked to a high potential for congenital deafness?

Answer

*Blazes* or *pandas*

Specific patterns of white markings, such as *blazes* or *panda* markings, carry a significant risk of congenital deafness, estimated to affect up to 75 percent of ferrets displaying them. This issue is related to a congenital defect that shares parallels with Waardenburg syndrome observed in humans. The underlying cause involves disruptions in pigment production during development that coincide with the formation of cranial structures. Specifically, the genetic mechanism affecting pigment creation in these areas can also interfere with the proper development of the inner ear structures responsible for hearing, demonstrating that visual traits can have hidden effects on complex sensory systems.

Which specific white patterning in ferrets is linked to a high potential for congenital deafness?
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