What genetic distinction separates a Dark-Eyed White (DEW) ferret from a true albino ferret?

Answer

DEWs possess dark eyes because their underlying genetic mechanism does not entirely block pigment production in the eyes

While both true albino ferrets and Dark-Eyed Whites (DEWs), sometimes called Black-Eyed Whites (BEWs), present with entirely white fur, the crucial difference lies in the eyes, which reflects distinct underlying genetic pathways. In a true albino, melanin production is almost completely shut down across the body, including the eyes, resulting in pink/red coloring. In contrast, the DEW has a genetic mechanism that results in pigment being expressed in the eyes, rendering them dark, even though the rest of the coat is white. This difference confirms that not all white coats are the result of the same genetic sequence responsible for total albinism.

What genetic distinction separates a Dark-Eyed White (DEW) ferret from a true albino ferret?

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