What specific gene mutation causes albinism in *Mustela putorius furo*?
Answer
Deletion in the TYR (tyrosinase) gene
The biological mechanism underlying albinism in ferrets is specifically identified as a deletion within the *TYR* (tyrosinase) gene. This deletion is the direct cause that prevents the animal's body from successfully producing melanin, the pigment responsible for coloration in the skin, hair, and eyes. The absence of melanin is the defining characteristic of true albinism, setting it apart from other color variations or white markings that might have different genetic origins.

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