What specific gene is often cited as the source of recessive mutation causing true albinism in ferrets?

Answer

The *tyrosinase* gene

True albinism in ferrets, characterized by the near or total absence of melanin, is generally attributed to a recessive genetic mutation, frequently cited as occurring within the *tyrosinase* gene. For a ferret to express this trait, it must inherit the specific mutated gene from both parents, as it is a recessive condition. Tyrosinase is an enzyme critical in the biochemical pathway responsible for melanin production. A deficiency or inactivity in this enzyme blocks the creation of the pigment that colors the fur, skin, and eyes, resulting in the signature snow-white appearance and lack of pigment in ocular structures.

What specific gene is often cited as the source of recessive mutation causing true albinism in ferrets?
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