What specific physical ailments are associated with the close family matings used to maintain the white coat lineage?
Crossed eyes (strabismus), immune deficiencies, spinal deformities, and kidney issues
The intensive captive breeding practices required to guarantee the expression of the white coat—which frequently necessitates mating closely related carriers—have resulted in severe negative health consequences for these animals. This inbreeding drastically concentrates deleterious recessive genes alongside the desired white gene. Common inherited defects observed in this population include crossed eyes, medically termed strabismus, which affects visual alignment. Furthermore, these tigers frequently suffer from compromised immune systems, structural problems like spinal deformities, and functional issues such as kidney problems. The visual appeal of the white coat is therefore often directly linked to significant compromises in the animal's overall long-term well-being.

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White Tigers - Get The FACTS! - YouTube