What dental anomaly is linked to the FOXI3 gene variant in Xolos besides hairlessness?

Answer

Hypodontia, or fewer teeth than normal

The genetic mechanism responsible for the hairless trait in the Xoloitzcuintli, specifically the FOXI3 gene variant, has pleiotropic effects, meaning it influences more than one phenotypic trait. One significant associated characteristic is the presence of dental anomalies. Specifically, the gene is linked to hypodontia, which medically refers to the condition of having fewer teeth than the typical full set for a dog. This often manifests as the absence of certain teeth, commonly including premolars. While the severity of this tooth reduction can vary among individuals within the breed, the incomplete set of teeth remains a common finding directly correlated with the dominant gene causing their defining physical characteristic.

What dental anomaly is linked to the FOXI3 gene variant in Xolos besides hairlessness?

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