Which specific advanced genetic manipulation technique is mentioned as being applicable to the mapped zebrafish genome?
Answer
CRISPR-Cas9
The zebrafish genome has been successfully mapped, meaning its entire sequence and gene locations are known. This comprehensive genetic map enables the precise application of modern genetic manipulation tools. Specifically, CRISPR-Cas9 is highlighted as a technique that can be used to modify specific genes with accuracy. Because the zebrafish embryos are readily accessible and their development is external, introducing these genetic modifications and observing the resulting effects is comparatively straightforward, allowing for the accurate creation of models simulating human genetic diseases.
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