Which species is commonly used as a reference point when identifying regions of the yak genome under strong positive selection?

Answer

*Bos taurus* (domestic cattle).

Modern genomic sequencing technologies allow researchers to compare the yak genome against that of other bovids to pinpoint evolutionary changes. When researchers seek to identify specific genetic regions that have undergone rapid adaptation in yaks—particularly those related to high-altitude survival, metabolic efficiency, and low-temperature adaptation—they frequently use the genome of *Bos taurus*, the domestic cattle, as the baseline comparison. This contrast highlights the specific genetic signatures that were strongly favored by natural selection in the yak lineage, resulting in substantial genomic differences between the two closely related groups.

Which species is commonly used as a reference point when identifying regions of the yak genome under strong positive selection?
evolutionyak