What causes the universal sterility observed in the zonkey hybrid?

Answer

Mismatched number and structure of chromosomes

The near-universal sterility found in zonkeys, similar to mules, is directly attributed to a chromosomal mismatch inherited from the two parent species. Zebras and donkeys, despite being compatible enough to produce offspring, possess different diploid chromosome counts. When the sperm and egg combine to form the zonkey zygote, the resulting cell contains an uneven and incompatible set of chromosomes. This structural difference prevents the correct pairing and segregation of chromosomes during meiosis, the essential cell division process required to produce functional gametes (viable sperm or eggs) for the next generation, thereby halting the perpetuation of the lineage naturally.

What causes the universal sterility observed in the zonkey hybrid?
animalclassificationsciencehybridZonkey