If a blister from Paederus dermatitis ruptures, what subsequent medical intervention might become necessary?

Topical or oral antibiotics to treat secondary bacterial infection

While the initial cause of Paederus dermatitis is chemical irritation from pederin, the resulting fluid-filled blisters (vesicles or bullae) are highly susceptible to secondary complications if they are scratched or rupture spontaneously. Scratching open these lesions introduces normal skin flora—bacteria—into the wound bed, leading to a superimposed bacterial infection, which is often a failure scenario if the patient scratches vigorously. Antibiotics, administered either topically or orally depending on severity, are necessary solely to manage these subsequent bacterial invasions. It is crucial to remember that antibiotics are ineffective against the initial viral or chemical reaction itself; their role is strictly limited to treating this secondary infection.