What is the severe consequence associated with Canine Cyclic Neutropenia (gray collie syndrome) in puppies?
Answer
Severely compromises a puppy's ability to fight illness
Canine Cyclic Neutropenia, also referred to as gray collie syndrome, is a particularly severe inherited blood disorder specific to Rough Collies. This condition directly impacts the bone marrow's production of neutrophils, which are a critical type of white blood cell essential for mounting an effective defense against bacterial and fungal infections. Because the neutrophil count cycles, creating periods of severe deficiency, puppies affected by CCN have their immune systems critically compromised, leaving them highly vulnerable to illness, which tragically often leads to death before they reach three years of age.

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