What is the primary functional deficiency that defines Exocrine Pancreatic Insufficiency (EPI) in Collies?
Answer
Severe malabsorption resulting in chronic diarrhea
Exocrine Pancreatic Insufficiency (EPI) is characterized by the pancreas failing to generate an adequate quantity of necessary digestive enzymes required to break down food components, particularly fats. This deficiency leads directly to severe malabsorption, meaning the dog cannot extract nutrients from its meals. Clinically, this manifests as weight loss despite a normal or increased appetite, chronic diarrhea, and a noticeably dry and flaky coat due to the inability to process dietary fats. Fortunately, EPI is manageable through the daily, lifelong addition of supplemental enzymes directly into the dog's food.
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