What is the primary function of the protein controlled by the MDR1 gene in the dog's physiology?
Answer
Acting as a protective pump in the blood-brain barrier
The MDR1 gene controls P-glycoprotein, which functions as a protective pump that eliminates certain toxins and medications before they can cause harm by preventing them from crossing the blood-brain barrier.
Related Questions
Which eye defect associated with Collies is a slow, progressive disease causing retinal deterioration?What is the primary function of the protein controlled by the MDR1 gene in the dog's physiology?What should owners of Collie mixes prioritize regarding the MDR1 mutation status?What condition is characterized by an abnormal formation of the joint socket and the head of the femur?What characterizes Collie Eye Anomaly (CEA) regarding when the condition manifests?Which medications are explicitly cited as commonly affected by the MDR1 mutation?What is a non-genetic management strategy recommended to help prevent orthopedic issues in growing Collie mixes?What systemic condition associated with Collies affects metabolism and can cause lethargy and skin problems?What term describes the hypothetical increased robustness sometimes seen in mixed breeds due to a broader gene pool?What life-threatening emergency shared with other deep-chested breeds requires immediate awareness from owners of Collie mixes?If a Collie is mixed with a breed already known for a specific orthopedic issue, what happens to the risk profile?