Which medications are explicitly cited as commonly affected by the MDR1 mutation?
Answer
Certain antiparasitics (like ivermectin) and some chemotherapy agents
The text specifies that drugs commonly affected when the MDR1 gene is defective include certain antiparasitics such as ivermectin, specific chemotherapy agents, and some pain medications.
Related Questions
Which eye defect associated with Collies is a slow, progressive disease causing retinal deterioration?What is the primary function of the protein controlled by the MDR1 gene in the dog's physiology?What should owners of Collie mixes prioritize regarding the MDR1 mutation status?What condition is characterized by an abnormal formation of the joint socket and the head of the femur?What characterizes Collie Eye Anomaly (CEA) regarding when the condition manifests?Which medications are explicitly cited as commonly affected by the MDR1 mutation?What is a non-genetic management strategy recommended to help prevent orthopedic issues in growing Collie mixes?What systemic condition associated with Collies affects metabolism and can cause lethargy and skin problems?What term describes the hypothetical increased robustness sometimes seen in mixed breeds due to a broader gene pool?What life-threatening emergency shared with other deep-chested breeds requires immediate awareness from owners of Collie mixes?If a Collie is mixed with a breed already known for a specific orthopedic issue, what happens to the risk profile?