Which two serious protein-wasting conditions is the Wheaten Terrier predisposed to?

Answer

Protein-Losing Enteropathy (PLE) and Protein-Losing Nephropathy (PLN).

The Soft-Coated Wheaten Terrier has a notable genetic predisposition toward two severe, distinct, protein-wasting syndromes that require diligent monitoring by owners. The first is Protein-Losing Enteropathy (PLE), where the gastrointestinal tract fails to retain necessary protein, resulting in symptoms such as swelling (edema), vomiting, and diarrhea; this condition is frequently linked to Inflammatory Bowel Disease within the breed. The second is Protein-Losing Nephropathy (PLN), where protein is lost through the kidneys, leading to symptoms like increased urination and thirst, along with edema. It is important to note that these conditions are related, as research indicates that PLE can sometimes develop subsequent to a diagnosis of PLN, highlighting the complexity of systemic protein regulation issues in this breed.

Which two serious protein-wasting conditions is the Wheaten Terrier predisposed to?
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