When picking up an anole, what action mimics a predatory strike?

Grabbing from above

When physical handling is necessary, the manner of approach is crucial to minimizing distress and preventing defensive reactions like tail dropping. Approaching an anole from directly above is strongly discouraged because, from the lizard's perspective, this posture precisely mimics the shadow and action of a bird or other aerial predator swooping down to capture prey. This innate fear response results in extreme fear and frantic attempts to escape. Therefore, veterinary guidelines and best practices advise scooping gently from underneath or approaching laterally to avoid triggering this powerful, instinctual alarm mechanism.