What approximate percentage of Collies are estimated to carry the predisposition related to the MDR1 Mutation?
Answer
Approximately 70%
The MDR1 (Multi-Drug Resistance) Mutation represents a significant health concern within the Collie breed, affecting how the dog metabolizes certain common medications. It is noted that approximately 70% of Collies carry a genetic predisposition that can result in adverse reactions if standard drug dosages are administered without accounting for this mutation. Responsible breeders make it a priority to test their stock for this condition. Identifying affected dogs allows veterinarians to safely adjust medication dosages, ensuring patient safety and avoiding toxic responses to necessary treatments.
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